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By John W. Boretos

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Largely because it has come from specialties of medicine which typically do not talk much to one another. Here we have made another attempt to bridge the gap. Orthodontists and maxillofacial surgeons, orthopedic surgeons, plastic surgeons, cardiovascular surgeons, nephrologists, pathologists and other medical specialties have joined with materials scientists and engineers, lawyers, regulators, manufacturers and medical business managers to discuss biomaterials—where we are and where we are going.

26:323-335, 1978. , Ill, Kouchoukos, N. , Karp, R. , Pacifico, A. D. and Kirklin, J. W. Late stenosis of Starr-Edwards cloth covered protheses. Ann. Thorac. Surg. 20:249-255, 1975. (8) Pierrie, W. , Hancock, W. , Koorajian, S. and Starr, A. Materials and heart valve prostheses. Ann. N. Y. Acad. Sd. 146:345, 1968. (9) Pluth, J. , Broadbent, J. , Barnhorst, D. A. and Danielson, G. K. Aortic and mitral valve replacement with cloth-covered Braunwald-Cutter prostheses. A three year follow up. Ann. Thorac.

J. Cardiol. 34:371, 1974. (12) Duma, R. J. (ed) Infections of Prosthetic Heart Valves and Vascular Grafts. University Park Press, Baltimore, 1977. Section II Properties, Structure, and Performance of Biomaterials Predicting Performance of Materials: Introductory Comments and Critique Alan S. Michaels Massachusetts Institute of Technology Cambridge, Massachusetts Lehigh University Bethlehem, Pennsylvania This conference topic addresses one of the most critical aspects of materials selection and development for in vivo prosthetic applications: namely, the identification and determination of the essential macroscopic mechanical, physical, and chemical properties of such materials; the establishment of relationships between these properties and the in vivo properties-requirements for specific prosthetic needs; and predicting the long-term performance characteristics of these materials under in vivo conditions.

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